Hydroxyzine for Dogs | Wag!

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Hydroxyzine for dogs is an antihistamine that relieves symptoms of allergic reactions. Hydroxyzine was created initially as a ataractic for humans. During clinical trials, researchers discovered hydroxyzine hydrochloride had the add profit of stopping allergic reactions. Further inquiry on hydroxyzine hydrochloride revealed its other applications as an anti-nausea and anti-anxiety medication and found that it was successful at treating these conditions in mammals besides humans. Though many other antihistamines have come out since its FDA approval, hydroxyzine hydrochloride is distillery one of the most normally official medications for allergic reactions and sedation in canines. Hydroxyzine ‘s mechanism of military action is like to other first-generation antihistamines in that it prevents histamine from binding to the receptors that instigate allergic responses. These antagonistic effects prevent mild symptoms like itching and sneezing, adenine well as more dangerous features like stomach spasms and air lane constriction. Besides being an antihistamine, hydroxyzine hydrochloride ‘s active metabolite besides suppresses neurological activity in mammals, making it an effective balmy tranquilizer.

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A typical dose of hydroxyzine hydrochloride for dogs is 1 milligram per ram between 1 and 3 times daily .

Dosage instructions

Administer hydroxyzine hydrochloride day by day as instructed by your vet. If your veteran prescribed this medicine on an as-needed footing, give it to your positron emission tomography at the beginning sign of an at hand episode .


A study of dogs treated with hydroxyzine hydrochloride and chlorpheniramine for atopic dermatitis observed no adverse side effects early than meek sleepiness in the sketch group. In this study, researchers scored the badness of the dogs ’ dermatologic symptoms before, during, and after discussion with hydroxyzine hydrochloride and chlorpheniramine. The data collected showed that this drug combination caused a 25 % improvement in dermatologic symptoms for many of the dogs .

Side effects

The side effects of hydroxyzine hydrochloride resemble those seen with early first-generation antihistamines like Benadryl. Side effects of hydroxyzine hydrochloride admit :

  • hyperactivity
  • Upset stomach
  • sleepiness
  • behavioral changes
  • sedation
  • excessive thirst
  • Loss of appetite
  • Balance issues
  • Seizures
  • trouble urinating
  • Tremors


Hydroxyzine ’ sulfur effects on certain neurotransmitters can adversely affect dogs with sealed conditions.

Anticholinergic drugs like hydroxyzine hydrochloride should alone be given to pets with epilepsy if medically necessity, since they can increase the likelihood of seizures. In dogs with congestive center failure, these anticholinergic effects can cause irregular heartbeat and worsen cardiovascular problems. This drug may exacerbate glaucoma due to its inhibitory effects on the neurotransmitter acetylcholine, which is responsible for pupil dilation and early eye functions. Because this medicate causes sedation, it ‘s not recommended for serve dogs since it can interfere with their ability to work. Discuss with your vet other non-drowsy alternatives for service animals. It ‘s unknown if curative doses of hydroxyzine hydrochloride for dogs are safe during canine pregnancy. Data shows that unusually high doses of this medicate are linked to congenital defects in animal models. Tell your vet if your pet becomes pregnant while taking this drug. This medicine isn ’ thyroxine recommended for nursing dogs, since it can dry up the milk add. Studies show the active metabolite of hydroxyzine hydrochloride does pass into human breast milk, though it ‘s unknown if this is true for canines or if it affects nurse puppies. Hydroxyzine should be besides used cautiously in dogs with urinary or intestinal blockages, nephritic disease, and impaired liver serve, since it can aggravate these conditions .

Drug interactions

Hydroxyzine magnifies the effects of sedatives and inhibits the effect of stimulatory medications. Inform your vet if your dog is taking any of these medications :

  • anticholinergic agents
  • skittish system depressants
  • epinephrine
  • Barbiturates
  • Sedatives

Allergic reactions and sensitivity

ironically, allergic reactions to antihistamines are actually quite common. Inform your vet of any past reactions to piperazine derivatives or first-generation antihistamines like Benadryl .

Frequently asked questions

What is the brand name of hydroxyzine for dogs?

The trade name names of this medicine are Vistaril and Restall, though generic versions ( like hydroxyzine hydrochloride pamoate ) are available. This drug was besides sold under Atarax and respective other names that are no long manufactured .

Can I give my dog other allergy medications with hydroxyzine?

Most vets advise against combining hydroxyzine hydrochloride with early antihistamines or tranquilizers since these can intensify sedation. Discuss other checkup alternatives with your veterinarian if you feel your cad needs something different .

When should I give hydroxyzine for my dog’s anxiety?

If your veterinarian prescribes this as an emergency medicate for panic attacks, distribute at the first signs of an at hand attack or before a nerve-racking situation. Outward signs of a panic attack include dilated pupils, trembling, fast pulse, hide, raised hair’s-breadth, and behavioral changes.

Is hydroxyzine a treatment for dermatitis?

Yes. Vets much prescribe hydroxyzine hydrochloride for dogs with dermatitis and antsy bark .

How long does hydroxyzine work for dogs?

typically the effects of this medication last for 6 to 8 hours .

Can I buy hydroxyzine for dogs without a prescription?

While some nonprescription meds contain hydroxyzine hydrochloride ( like certain types of Dramamine ), it ‘s unknown if these are condom for dogs. Do not give nonprescription formulations of hydroxyzine hydrochloride unless your vet deems them safe for your pet .

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